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岩芪系百合科开口箭属植物开口箭(Jupistra chinensis Baker),民间用于治疗白喉、风湿、狂吠咬伤,毒蛇咬伤、胃肠炎等。笔者以岩芪为主药,组成方剂QE-8407,进行抗癌药理、临床试验,证明对W256等瘤株有抑制作用。为搞清主药岩芪的化学成分,笔者进行了提取分离工作。通过柱层析及薄层层析分离、鉴定证明,含有甾体、有机酸、酚、多糖、鞣质、挥发油等组分。通过紫外,红外等分析、所得五个结晶中,其中三个结晶可能为28烷、藻朊酸、和D-(-)-Erythrose,准确化学结构的测定,有待进一步工作。
Litchi is a family of Jupistra chinensis Baker. It is used for the treatment of diphtheria, rheumatism, manic bites, snake bites, and gastroenteritis. The author to Yanqi as the main drug, composed of prescription QE-8407, anti-cancer pharmacology, clinical trials, proved to inhibit W256 and other tumor strains. In order to find out the chemical composition of the main medicine, Iridium, the author carried out the extraction and separation work. Separation and identification by column chromatography and thin layer chromatography showed that it contained steroids, organic acids, phenols, polysaccharides, tannins, and volatile oils. Analysis of the five crystals obtained by UV, IR, etc., among which three crystals may be 28 alkane, alginic acid, and D-(-)-Erythrose, the exact chemical structure of the determination, pending further work.