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牛肺表面活性剂-TA(简称TA)已用于治疗新生儿呼吸窘迫综合征,然而用于成人的报道甚少。本文报道治疗成人呼吸衰竭的疗效.例1 女性66岁为烧伤所致的成人呼吸窘迫综合征(ARDS),经从气管插管注入TA 240 mg,于住院第4天行首次治疗后FiO_2为1.0时,治疗后40分钟PaO_2(mmHg)从57升至104,4小时升至159;次日行第2次治疗1小时后PaO_2增加16mm Hg.经2次治疗后胸部X 线检查显示肺损害改善。治疗后第6天因吸入性肺炎呼吸困难及痰增多,相继又给TA
Bovine pulmonary surfactant-TA (TA) has been used to treat neonatal respiratory distress syndrome, however, little is reported for adults. This article reports the efficacy of treatment of respiratory failure in adults.Example 1 A 66-year-old female adult with respiratory distress syndrome (ARDS) who underwent burns received TA 240 mg intratracheal intubation and FiO_2 1.0 , PaO 2 (mmHg) increased from 57 to 104,4 hours at 40 minutes after treatment and rose to 159 at 40 minutes after treatment; PaO 2 increased by 16 mm Hg at 1 hour after the second day of treatment on the following day. Chest radiographs showed improvement in lung damage after 2 treatments . 6 days after treatment of aspiration pneumonia dyspnea and sputum increased, have given to TA