论文部分内容阅读
目的：观察乌拉地尔预防全麻诱导引起的病人血压升高的效果。方法：选择３０ 例择期手术气管内全麻病人（ 男性１８ 例，女性１２ 例，年龄５７ ａ ±ｓ１１ ａ， 体重６２ ｋｇ ±７ ｋｇ） ， 用乌拉地尔在麻醉诱导前按０ ．４ ｍｇ／ｋｇ 加入５ ％ 葡萄糖注射液稀释成１０ｍＬ进行静脉注射。观察病人收缩压（ＳＢＰ） 、舒张压（ＤＢＰ） 、平均动脉压（ ＭＡＰ） 、心率（ＨＲ） 和脉搏血氧饱和度（ＳＰＯ２） 。结果：与基础值相比，注射乌拉地尔后ＳＢＰ，ＤＢＰ，ＭＡＰ，均有不同程度下降（ Ｐ＜ ０ ．０５或Ｐ＜ ０ ．０１） ，ＨＲ 和ＳＰＯ２ 无明显差别（ Ｐ＞ ０ ．０５） 。气管插管时ＳＢＰ，ＤＢＰ，ＭＡＰ 和ＳＰＯ２ 无明显差别（ Ｐ＞ ０ ．０５） ， ＨＲ 升高（ Ｐ＜ ０ ．０１） 。结论：全麻诱导前用乌拉地尔可以预防全麻诱导中血压升高。
Objective: To observe the effect of Urapidil in preventing the increase of blood pressure in patients induced by general anesthesia. Methods: Totally 30 patients undergoing general anesthesia for tracheal intubation (18 males, 12 females, 57 a ± s11 a, weighing 62 kg ± 7 kg) were enrolled in this study. Urapidil was given 0 before induction of anesthesia. 4 mg / kg added 5% glucose injection diluted to 10mL for intravenous injection. Patient SBP, DBP, MAP, heart rate (HR) and pulse oxygen saturation (SPO2) were observed. Results: SBP, DBP and MAP decreased significantly (P <0.05 or P <0.01) compared with the baseline values, but there was no significant difference between HR and SPO2 (P> 0.05) . There were no significant differences in SBP, DBP, MAP and SPO2 during tracheal intubation (P> 0.05) and HR (P <0.01). CONCLUSIONS: Urapidil before general anesthesia can prevent elevated blood pressure during induction of general anesthesia.