在体外模拟人体消化环境,以降血脂药物考来烯胺为对照,比较了经不同处理的中华芦荟与胆酸盐的结合能力,发现芦荟具有较强的结合胆酸盐的能力,其中黄酮类成分与胆酸盐的结合能力较强,且芦荟结合胆酸盐能力与黄酮类物质含量呈显著性正相关关系,而蒽醌类和多糖类物质的含量变化对芦荟结合胆酸盐的能力影响不显著。通过相关性分析初步判断了芦荟中结合胆酸盐的主要活性成分为黄酮类物质,且结合能力随黄酮的量呈正相关的关系。 In vitro simulation of the human digestive environment, to lipid-lowering drugs test for enamine as a control, compared the different treatment of Chinese aloe and cholate binding ability and found that aloe has a strong ability to bind cholate, of which flavonoids And bile salts strong binding ability, and aloe combined with cholate ability and flavonoid content was significantly positive correlation, and anthraquinones and polysaccharides content of aloe combined with cholate ability Not obvious. Through the correlation analysis, the main active component of the combined cholate in aloe was determined to be flavonoids, and the binding ability was positively correlated with the amount of flavonoids.