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目的 :验证促孕胶囊Ⅲ号治疗高催乳素引起的不孕 (育 )症的临床作用与疗效。 方法 :选择符合条件的高催乳素血症 (HPRL) 2 0 0例 ,双盲随机分甲乙两组 ,各 10 0例 ,比较两组的疗效 ;并于治疗前后检测催乳素 (PRL)、雌二醇 (E2 )、睾酮 (T)或黄体酮 (P) ,比较治疗前后及组间激素的变化 ,同时分析 2 0 0例HPRL的临床表现与辨证分型。结果 :甲 (中药 )组与乙 (溴隐亭即CB154 )组疗效差异不显著 (P >0 .0 5 ) ;用药 3个月后 ,测定PRL明显下降 ,E2 、T或P明显改变 ,较治疗前有显著性差异 ;停药追踪 3个月 ,中药组复发率低于CB154 组。中药辨证分析 ,HPRL以肝郁为主 ,肾虚或脾虚多见。 结论 :促孕胶囊Ⅲ号能抑制血PRL和调节E2 、T或P等激素 ,其特点是便、廉、验、无毒副反应 ,具有疏肝、补肾健脾之功 ,是治疗HPRL引起的不孕不育症的高效浓缩中药。
Objective: To verify the clinical effect and curative effect of promoting pregnancy capsule Ⅲ in treating infertility induced by high prolactin. Methods: Two hundred and seventy patients with hyperprolactinemia (HPRL) were selected. The patients were randomly divided into two groups (100 cases in each group), and their prolactin (PRL) and estradiol (E2), testosterone (T) or progesterone (P). The changes of hormones before and after treatment and between groups were compared. Meanwhile, the clinical manifestations and syndrome differentiation of 200 HPRL were analyzed. Results: There was no significant difference in efficacy between A (Chinese medicine) group and B (CB154) group (P> 0.05). After three months of treatment, PRL decreased obviously and E2, T or P changed obviously Before treatment there was a significant difference; withdrawal drug tracking 3 months, the Chinese medicine group recurrence rate was lower than the CB154 group. TCM syndrome differentiation, HPRL mainly liver depression, kidney or spleen more common. Conclusion: Capsule No. Ⅲ can inhibit the blood PRL and regulate E2, T or P and other hormones, which is characterized by convenient, inexpensive, experience, non-toxic side effects, with Shugan, kidney and spleen of the power, is the treatment of HPRL Infertility of highly concentrated traditional Chinese medicine.