目的:探究医院门诊西药房的不合格处方点评情况分析与原因调查研究。方法:收集我院2015年10月-2016年10月门诊医药房开出的1235张处方,对其不合理处方原因进行回顾性分析。结果:在1235张处方中,共有104张不合格处方,其产生的主要原因包括药物选择不当、联合用药不合理、溶媒选择不当、药物剂量不当、给药次数及方法不当、用药间隔时间不合理。结论:结合不合理用药因素分析,通过强化要用制度、严格审核处方、增强药剂师职业道德等,以减少不合理用药情况,确保患者的用药安全。 Objective: To investigate the situation analysis and cause investigation of unqualified prescriptions in western outpatient pharmacy. Methods: A total of 1235 prescriptions from outpatient pharmacies in our hospital from October 2015 to October 2016 were collected retrospectively. Results: Of the 1235 prescriptions, there were 104 unqualified prescriptions. The main reasons for this include improper drug selection, improper combination therapy, improper solvent selection, improper dosage of drugs, improper dosing times and methods, unreasonable interval of medication . Conclusion: In combination with the analysis of irrational drug use factors, the system of drug use should be strengthened, the prescriptions should be strictly examined and the professional ethics of pharmacists be enhanced to reduce irrational drug use and ensure the safety of patients.