目的　探讨自体腓骨头及同种异体骨在桡骨远端骨巨细胞瘤临床治疗中的应用和疗效。方法　采用自体同侧腓骨头及深低温冷冻同种异体骨 ,在桡骨远端骨巨细胞瘤瘤段切除后建腕关节。自体腓骨头取材时保留侧付韧带及关节囊并术中重建 ,接骨端做成梯形增加接骨端接触面 ,短四孔钢板骨固定 ,用克氏针固定于腕关节功能位 ,石膏夹外因定 8周。结果　随访 1年以上 ,未见术后肿瘤复发 ,所有骨移植体X线片上显示理想的替代形态。本组 5例应用自体腓骨头重建腕关节 ,2例同种异体桡腕关节重建 ,关节无疼痛 ,外观基本满意。两种方法术后关节活动度无差异 ;能达到旋前 40°、旋后 5 0°、背伸 40°、掌屈 5 0°。结论　上述两种方法 ,能防止肿瘤复发 ,同时术后腕关节有好的功能 Objective To investigate the clinical application of autologous fibular head and allogenic bone in the treatment of giant cell tumor of distal radius. Methods The autologous ipsilateral fibula head and cryogenic frozen allograft were used to establish the wrist joint after excision of the giant cell tumor of the distal radius. The autologous fibula head was taken to retain the lateral ligament and the articular capsule and reconstruction, the trabecular end made trapezoidal increase the contact surface of the end of the bone, the short four-hole plate fixation, with Kirschner wire fixed in the wrist position, plaster external factors 8 weeks. The results were followed up for more than 1 year, no tumor recurrence after surgery, all bone graft X-ray showed an ideal alternative morphology. The group of 5 patients with autologous fibular head reconstruction of the wrist, 2 cases of allograft reconstruction of the radial wrist, joint pain, the appearance of basic satisfaction. There was no difference between the two methods in postoperative mobility of the joints; it reached 40 ° pronation, 50 ° pronation, 40 ° dorsiflexion and 50 ° palmar flexion. Conclusion The above two methods can prevent tumor recurrence, and have good function of the wrist after operation