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目的:分析学龄前2~6岁肥胖儿童的血脂水平,为心血管疾病的早期预防提供依据。方法:对79例肥胖儿童和96例正常体重儿童清晨空腹抽取静脉血测定甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、载脂蛋白AⅠ(apoAⅠ)、载脂蛋白B(apoB)。结果:肥胖组儿童TC、TG、LDL-C、APOB均高于正常体重儿童,HDL-C、APO-A均低于正常体重儿童(P值均<0.05)。肥胖儿童高脂血症检出率高于对照组,差异有统计学意义(P<0.05)。结论:肥胖儿童学龄前即可出现血脂代谢异常,应加强血脂监测并及早干预。
Objective: To analyze the blood lipid levels of obese children aged 2 ~ 6 years old and provide the basis for the early prevention of cardiovascular diseases. Methods: Serum triglyceride (TG), total cholesterol (TC), high density lipoprotein cholesterol (HDL-C) and low density lipoprotein cholesterol (LDL) were measured in fasting venous blood of 79 obese children and 96 normal- -C), apolipoprotein AI (apo AI), apolipoprotein B (apoB). Results: The levels of TC, TG, LDL-C and APOB in obese children were significantly higher than those in normal weight children. The levels of HDL-C and APO-A in obese children were lower than those in normal weight children (P <0.05). The detection rate of hyperlipidemia in obese children was higher than that in control group, with significant difference (P <0.05). Conclusion: Obese children may have dyslipidemia when they are preschool aged, blood lipid monitoring and early intervention should be strengthened.