论文部分内容阅读
目的 :观察采用中西医结合方法治疗肝移植术后多器官功能障碍综合征 (MODS)疗效 ,探讨中西医结合治疗危重病的优势。方法 :5 4例肝移植术后并发 MODS患者 ,随机给予西医常规治疗及中西医结合治疗并根据预后分为存活组和死亡组 ,记录急性生理和慢性健康状况评分 (APACHE ) ,对病死率进行分析。结果 :5 4例患者 APACHE 均值显著高于总体均值 (P<0 .0 1)。存活组中药“血必净”用量、感染清除率、弥散性血管内凝血 (DIC)改善率、连续性静静脉血液滤过 (CVVHF)应用时间均明显高于死亡组 (P均 <0 .0 5 ) ;而呼吸机使用时限低于死亡组 (P<0 .0 5 ) ;中心静脉压 (CVP)、肺动脉楔压 (PAWP)均无显著差异 (P均 >0 .0 5 )。结论 :中西医结合治疗肝移植术后 MODS可改善临床指标 ,明显降低其病死率。
Objective: To observe the treatment of multiple organ dysfunction syndrome (MODS) after liver transplantation by combining traditional Chinese and western medicine and explore the advantages of combining traditional Chinese and western medicine in the treatment of critical illness. Methods: Fifty-four patients with MODS who underwent liver transplantation were randomly divided into two groups: conventional treatment with western medicine and traditional Chinese medicine combined with Western medicine. According to the prognosis, they were divided into survival group and death group. Acute Physiology and Chronic Health Status Score (APACHE) analysis. Results: The mean APACHE in 54 patients was significantly higher than the overall mean (P <0.01). Survival group “Xuebijing net” dosage, infection clearance, disseminated intravascular coagulation (DIC) improvement rate, continuous venous hemofiltration (CVVHF) application time were significantly higher than the death group (P <0. 0 (P <0.05). There were no significant differences in CVP and PAWP between the two groups (all P> 0.05). Conclusion: Integrative treatment of MODS after liver transplantation can improve clinical indicators, significantly reducing the mortality.