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目的建立一个规范化、标准化的肝炎病毒(HBV)感染患者和对照组标本库。方法通过对四川绵阳地区大型流行病调查,收集HBV感染患者捐赠的血液标本(ELISA)检测调查者血样乙肝表面抗原(HBsAg),完整记录其实验报告,临床干预及流行病学调查资料。结果重大专项传染病综合防治四川示范区项目启动至今共收集血液组织标本87 478份,其中HBV检出阳性标本60 571份;保留相关阴性对照标本26 907份。结论建立HBV感染患者及对照组血液标本库,可为乙肝的综合防治与研究提供高质量标本及相关流行病调查信息。
Objective To establish a standardized and standardized database of patients infected with hepatitis B virus (HBV) and control samples. Methods The blood samples (HBsAg) from donors were collected from the patients with HBV infection in the survey of large-scale epidemic diseases in Mianyang, Sichuan Province. The HBsAg of the blood samples were collected and the experimental reports, clinical interventions and epidemiological investigation data were recorded intact. Results A total of 87 478 blood samples were collected from the project of Sichuan Demonstration Zone for the Comprehensive Prevention and Control of Major Special Infectious Diseases. Among them, 60 571 positive samples were detected by HBV, and 26 907 negative samples were reserved. Conclusion The establishment of a blood bank in patients with HBV infection and the control group can provide high-quality specimens and relevant epidemiological investigation information for the comprehensive prevention and treatment of hepatitis B.