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目的分析肺平滑肌瘤病的临床、病理学特征及组织起源。方法通过光镜及免疫组化观察并结合临床资料及相关文献复习,探讨肺平滑肌瘤病的临床病理学特征、鉴别诊断及组织起源。结果患者中年女性,有子宫平滑肌瘤病史,双肺多发小结节样病变;经开胸肺活检,结合组织形态及免疫组化显示为平滑肌源性肿瘤,参考文献及临床病理特点,最后诊断为肺平滑肌瘤病。结论肺平滑肌瘤病是一种少见的肺内良性肿瘤,患者多为中年女性,有子宫平滑肌瘤病史,组织起源不清,预后良好。
Objective To analyze the clinical and pathological features of lung leiomyomata and its origins. Methods By light microscopy and immunohistochemistry combined with clinical data and literature review, to explore the clinical pathological features of pulmonary leiomyomata, differential diagnosis and tissue origin. Results The middle-aged women had a history of uterine leiomyoma and multiple nodules-like lesions in lung. Thoracic and pulmonary biopsy, combined with histomorphology and immunohistochemistry showed smooth muscle-derived tumors, references and clinicopathological features, and finally Diagnosis of pulmonary leiomyoma disease. Conclusions Pulmonary leiomyoma is a rare benign intrapulmonary neoplasm. Most of the patients are middle-aged women, with a history of uterine leiomyoma, unclear tissue origin and good prognosis.