目的:探讨复发性流产(RSA)患者子宫动脉血流超声的血流参数及频谱波形的特征。方法:共纳入87例早孕妇女,其中有RSA史妇女41例,无流产史早孕妇女(对照组)46例,所有对象均行阴道超声多普勒测量子宫动脉血流参数,测量指标有:收缩期峰值流速/舒张末期流速(S/D)、搏动指数(PI)、阻力指数(RI)。随访妊娠结局,排除无流产史妇女中发生难免流产者。根据受试者工作曲线(ROC)比较各参数诊断价值,另将子宫动脉波形进行分类,同时比较RSA组和对照组波形的分布差异。结果:正常对照组排除难免流产7例后为39例。RSA组患者平均年龄29.7±3.4岁,正常对照组28.2±4.2岁。RSA组的子宫动脉S/D、PI、RI分别为6.98±1.67、1.46±0.12、0.84±0.04;正常对照组分别为5.30±1.05、1.31±0.15、0.81±0.12。RSA组的子宫动脉S/D与PI均高于对照组,差异有统计学意义,RI值组间差异无统计学意义(P>0.05)。ROC曲线下面积三者均>0.8,其中以PI最大;血流频谱波形A、0型的发生率较对照组高。结论:RSA患者的S/D、PI明显高于正常早孕妇女,高阻力血流波形发生率明显高于正常早孕妇女。 Objective: To investigate the characteristics of blood flow parameters and spectral waveforms of uterine arterial blood flow in patients with recurrent spontaneous abortion (RSA). METHODS: A total of 87 early pregnant women were enrolled, including 41 women with RSA history and 46 women with no history of early pregnancy (control group). All subjects underwent vaginal ultrasound Doppler measurement of uterine arterial blood flow parameters. The indexes of measurement included: Peak flow / end-diastolic flow rate (S / D), pulsatility index (PI), resistance index (RI). Follow-up of pregnancy outcomes, excluding women without abortion in the inevitable occurrence of abortion. According to the receiver operating characteristic curve (ROC), the diagnostic value of each parameter was compared, and the uterine artery waveform was also classified. At the same time, the differences of waveform distribution between RSA group and control group were compared. Results: In the control group, 39 cases were excluded after 7 cases of unavoidable abortion. The mean age of patients in RSA group was 29.7 ± 3.4 years and that in normal control group was 28.2 ± 4.2 years. The S / D, PI and RI of uterine arteries in RSA group were 6.98 ± 1.67, 1.46 ± 0.12 and 0.84 ± 0.04, respectively. The normal control group were 5.30 ± 1.05, 1.31 ± 0.15 and 0.81 ± 0.12 respectively. The S / D and PI of uterine arteries in RSA group were higher than those in control group, and the difference was statistically significant. There was no significant difference between RI groups (P> 0.05). The area under the curve of ROC were all> 0.8, of which the PI was the largest; the frequency of waveform A and type 0 of blood flow was higher than that of the control group. Conclusion: The S / D and PI of RSA patients were significantly higher than those of normal pregnant women. The incidence of high resistance blood flow waveform was significantly higher than that of normal pregnant women.