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目的对比分析“萤火虫”成像技术和二维高频超声显示甲状腺内细砂粒样钙化对甲状腺乳头状癌诊断的临床意义。方法选取我院甲状腺外科2010年1月～2010年7月128例甲状腺结节手术患者(共计160个结节),良性结节96个,恶性结节64个,其中甲状腺乳头状癌结节63个,甲状腺髓样癌结节1个。术前患者均进行甲状腺二维高频超声及“萤火虫”成像技术检查,重点观察甲状腺结节内有无细砂粒样钙化,诊断甲状腺乳头状癌,并与术后病理结果对照分析。结果二维高频超声检出甲状腺内细砂粒样钙化诊断甲状腺乳头状癌的敏感性54.0%(34/63)、特异性78.4%(76/97)、精确度68.8%(110/160);“萤火虫”成像技术诊断甲状腺癌的敏感性81.0%(51/63)、特异性81.4%(80/97)、精确度81.3%(130/160)。两者对比有显著差异性(P<0.05)。结论 “萤火虫”成像技术在检出细砂粒样钙化诊断甲状腺乳头状癌的敏感性、特异性、精确度均高于二维高频超声。
Objective To comparatively analyze the clinical significance of “gossamer” imaging and two-dimensional high-frequency ultrasound in the diagnosis of thyroid papillary carcinoma with fine-grained calcification in the thyroid gland. Methods A total of 128 patients with thyroid nodules (total 160 nodules), 96 benign nodules and 64 malignant nodules were selected from January 2010 to July 2010 in our hospital. Thyroid papillary carcinoma nodules 63 A, medullary thyroid carcinoma nodules 1. Preoperative patients were performed two-dimensional high-frequency thyroid ultrasound and “firefly” imaging examination, focusing on thyroid nodules with or without fine-grained calcification, diagnosis of papillary thyroid carcinoma, and postoperative pathological results of controlled analysis. Results The sensitivity and accuracy of two - dimensional high - frequency ultrasonography in diagnosing papillary thyroid carcinoma were 54.0% (34/63), 78.4% (76/97) and 68.8% (110/160) respectively. The sensitivity of firefly imaging in the diagnosis of thyroid cancer was 81.0% (51/63), specificity was 81.4% (80/97) and the accuracy was 81.3% (130/160). There was significant difference between the two (P <0.05). Conclusion “Firefly” imaging technique is more sensitive, specific and accurate in detecting papillary thyroid carcinoma with fine gritty calcification than 2D high frequency ultrasound.