CYP2 C9为细胞色素 P450超家族酶的一个成员 ,与 S-华法令水解有关并从循环中迅速清除。已知有两种等位基因变异型 - CYP2 C9* 2和CYP2 C9* 3。Aithal和 Steward及其同事报告这些变异可以导致 S-华法令代谢降低。这些变异型携带者代谢法华令较野生型代谢缓慢 ,可导致血浆华法令 CYP2 C9 is a member of the cytochrome P450 superfamily enzyme that is involved in S-warfarin hydrolysis and is rapidly cleared from the circulation. Two allelic variants are known - CYP2 C9 * 2 and CYP2 C9 * 3. Aithal and Steward and colleagues report that these mutations can lead to reduced S-warfarin metabolism. Metabolite Fahrenheit is more slowly metabolized than wild type in these variant carriers and can cause warfarin