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目的:探讨分子影像SPECT/CT对乳腺癌骨转移的临床应用价值。方法 :回顾性分析多层螺旋CT与SPECT/CT融合显像对68个疑似乳腺癌骨转移病灶的检查结果,进行统计学检验。结果:经临床确诊乳腺癌骨转移的55个病灶中:MSCT诊断的敏感度为78.2%(43/55),特异性为92.3%(12/13),准确性为80.9%(55/68);SPECT/CT融合显像诊断敏感度为96.4%(53/55),特异性为76.9%(10/13),准确性为92.6%(63/68)。2种检查方法的敏感度、准确性差异有统计学意义(P<0.05),特异性差异无统计意义。结论:SPECT/CT融合显像相对于MSCT检查,可提高对乳腺癌骨转移的诊断敏感性和准确性,具有较好的临床应用价值。
Objective: To investigate the clinical value of molecular imaging SPECT / CT in breast cancer patients with bone metastasis. Methods: The results of 68 cases of suspected bone metastases from breast cancer were analyzed retrospectively by multislice spiral CT and SPECT / CT fusion imaging. Statistical analysis was performed. Results: Of the 55 lesions with clinically diagnosed breast cancer bone metastases, the diagnostic sensitivity of MSCT was 78.2% (43/55), the specificity was 92.3% (12/13) and the accuracy was 80.9% (55/68) The diagnostic sensitivity of SPECT / CT fusion imaging was 96.4% (53/55), the specificity was 76.9% (10/13) and the accuracy was 92.6% (63/68). The sensitivity and accuracy of the two methods were statistically significant (P <0.05), but the specificity was not statistically significant. Conclusion: Compared with MSCT, SPECT / CT fusion imaging can improve the sensitivity and accuracy of diagnosis of bone metastasis of breast cancer and has good clinical value.