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目的:分析研究2型糖尿病周围神经病变采取α-硫辛酸以及甲钴胺进行治疗的方法以及治疗效果,为临床提供有力的依据。方法:选取我院在2015年1月到2016年1月所收治的2型糖尿病周围神经病变患者资料100例开展回顾性分析,将所选取的100例患者依照其入院顺序分为两组,平均每组50例,其中对照组50例患者接受甲钴胺治疗,研究组50例患者接受α-硫辛酸治疗,两组患者全部治疗1个月,统计研究组和对照组患者治疗效果,比较两组患者治疗之前以及治疗之后的神经传导速度,将所得数值进行统计学分析。结果:研究组和对照组患者治疗之前的神经传导速度对比没有统计学意义(P>0.05);治疗之后,研究组患者神经传导速度以及治疗效果显著高于对照组,两组比较存在统计学意义(P<0.05)。结论:对于2型糖尿病周围神经病变患者采取α-硫辛酸治疗效果明显优于甲钴胺,能够有效提高患者神经传导速度,应该在临床中大力推广使用。
OBJECTIVE: To analyze the methods and the therapeutic effects of α-lipoic acid and mecobalamin for the treatment of type 2 diabetic peripheral neuropathy and to provide a strong evidence for clinical practice. Methods: A retrospective analysis of 100 patients with type 2 diabetic peripheral neuropathy admitted to our hospital from January 2015 to January 2016 was conducted. The selected 100 patients were divided into two groups according to their admission order, with an average of 50 patients in each group, of which 50 patients in the control group received mecobalamin treatment, 50 patients in the study group were treated with α-lipoic acid, and both groups were treated for 1 month. The treatment effect was compared between the study group and the control group Group of patients before treatment and after treatment of nerve conduction velocity, the values obtained for statistical analysis. Results: There was no significant difference in the nerve conduction velocity between the study group and the control group before treatment (P> 0.05). After the treatment, the nerve conduction velocity and the therapeutic effect in the study group were significantly higher than those in the control group (P <0.05). Conclusion: The treatment of α-lipoic acid in patients with type 2 diabetic peripheral neuropathy is superior to mecobalamin, which can effectively improve the nerve conduction velocity in patients and should be widely promoted in clinic.