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目的 探讨沂蒙山区吸入性变应原的种类与儿童过敏性哮喘的关系 ,针对性的进行防治 ,使哮喘的发病率降低到最低范围。方法 采用北京协和医院变态反应科提供的变应原原液及上海医科大学提供的家蝇、悬铃木、艹律 草、猫毛、狗毛变应原原液 ,选用前臂屈侧皮肤点刺法对哮喘儿童进行吸入性过敏原皮肤试验。 结果 阳性率为 5 3.0 4 % (2 4 4/ 4 6 0 )。其中屋尘占 6 1.0 7% (14 9/2 4 4) ,尘螨占 6 0 .6 6 % (14 8/ 2 4 4) ;多价昆虫占 4 3.0 3% (10 5 / 2 4 4) ;多价真菌I、II、III分别占2 7.87% (6 8/ 2 4 4)、33.2 0 % (81/ 2 4 4)、2 7.87% (6 8/ 2 4 4) ;春季花粉I、II、III分别占 2 9.92 % (73/2 4 4) ;31.97% (78/ 2 4 4)、;2 0 .4 9% (5 0 / 2 4 4) ;香烟烟占 2 5 .82 % (6 3/ 2 4 4) ;桑蚕丝占 19.6 7% (48/2 4 4) ;多价羽毛占 18.4 4% (45 / 2 4 4) ;棉絮占 13.11% (32 / 2 4 4) ;猫毛占 9.83% (2 4 / 2 4 4) ;狗毛占6 .15 % (15 / 2 4 4)。结论 沂蒙山区儿童过敏性哮喘与吸入性变应原有直接关系 ,主要引起儿童哮喘的变应原有屋尘 ,尘螨、多价真菌、春季花粉、夏秋花粉、蒿草花粉。香烟烟、桑蚕丝及羽毛和兽毛也是引起哮喘的主要变应原
Objective To explore the relationship between allergic asthma and allergic asthma in Yimeng mountainous area, and to prevent and cure asthma in order to reduce the incidence of asthma to a minimum. Methods The allergen fluid supplied by the Department of Allergy, Peking Union Medical College Hospital and the housefly, Platanus, Arborvitae, cat’s hair and dog’s hair allergen stock solution provided by Shanghai Medical University were used in this study. Perform inhaled allergen skin test. The positive rate was 5 3.0 4% (2 4 4/4 6 0). Among them, house dust accounted for 6 1.07% (14 9/2 4 4), dust mites accounted for 60.66% (14 8/2 4 4), and polygamous insects accounted for 4 3.03% (105/1444) ), Respectively; the polyvalent fungi I, II, and III accounted for 7.887% (68/244), 33.2% (81/224) and 2 7.87% (68/244), respectively; , II, III accounted for 29.92% (73/244), 31.97% (78/244), and 20.49% (50/244) respectively. Cigarette smoke accounted for 25.82 The percentage of mulberry silk was 19.6 7% (48/2 4 4), that of multivalent feathers was 18.4 4% (45/244), that of cotton was 13.11% (32/244) ; Cats accounted for 9.83% (2 4/244); Dogs accounted for 6.15% (15/244). Conclusion There is a direct relationship between allergic asthma and inhaled allergens in Yimeng mountainous area. There are house dust, dust mites, polyvalent fungi, spring pollen, summer and autumn pollen and wormwood pollen in allergens of children asthma. Cigarette smoke, silk and feathers and animal hair are also the major allergens that cause asthma