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5. Role of C5a-C5aR axis in the development of atherosclerosis

Role of C5a-C5aR axis in the development of atherosclerosis

来源 :中国科学：生命科学英文版 | 被引量 : 0次 | 上传用户：tenghua303

【摘 要】

：

Complement component 5a(C5a)is a 74 amino acid glycoprotein and an important proinflammatory mediator that is cleaved enzymatically from its precursor,C5,on act

【作 者】

：

AN GuiPeng REN GuoRui AN FengS 

【机 构】

：

KeyLaboratoryofCardiovascldarRemodelingandFullctionResearch,DetpartmentofCardiology,DepartmentofGeri

【出 处】

：

中国科学：生命科学英文版

【发表日期】

：

2014年8期

【关键词】

：

动脉粥样硬化 轴线 实验动物模型 生物效应 免疫应答 人体器官 血管疾病 动脉硬化 C5a C5a receptors atherosclerosis 

【基金项目】

：

supported by the National Natural Science Foundation of China（81000125,81000127）, Specialized Research Fund for the Doctoral Program of Higher Education（20100131120057）, Promotive Research Fund for Yo

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论文部分内容阅读

Complement component 5a(C5a)is a 74 amino acid glycoprotein and an important proinflammatory mediator that is cleaved enzymatically from its precursor,C5,on activation of the complement cascade.C5a is quickly metabolised by carboxypeptidases,forming the l

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