多发性骨髓瘤(MM)合并类风湿性关节炎(RA),临床罕见,并伴有巨大胸壁肿块者未见有报道,现报道1例如下:严某,女性,55岁,工人,三十年前因反复四肢大小关节肿痛,僵硬等,在上海某市级医院确诊为类风湿性关节炎(RA)。病程中曾反复检查类风湿因子,抗核抗体阳 Multiple myeloma (MM) combined with rheumatoid arthritis (RA), a rare clinical, accompanied by a huge chest wall mass who have not been reported, is reported as follows: Yan, a woman, 55 years old, workers, thirty Years ago due to repeated joint size and joint swelling and pain, stiffness, etc., was diagnosed with rheumatoid arthritis (RA) in a municipal hospital in Shanghai. Rheumatoid factor has repeatedly check the course of anti-nuclear antibody Yang