论文部分内容阅读
《中成药研究》1983年第6期刊登的内蒙古自治区中蒙医研究所顾维彰、邓丽嘉同志写的“紫外光谱法测定生脉注射液”一文,我们看了后觉得有不妥的地方,特提出来,与作者商榷。该文提出用紫外光谱法可快速、简单地测定生脉注射液中的人参与麦冬皂甙总含量,这显然是不妥当的。人参的主要成分为人参总皂甙(Ginsenosides),根据人参皂甙元的结构不同,可将人参皂甙分为人参皂甙A、B、C三种类型。从它们的分子结构可看出,分子中并没有共轭双键存在,因而,在200～400nm波长范围就没有紫外吸收光谱。为此,目前国内外在测定人参及其制剂中的人参皂甙的含量时,都采用重量法、比色法、薄层比色法、
In “Chinese Medicine Research”, published in the 6th issue of 1983, the article “Ultraviolet Spectrometric Determination of Shengmai Injection” written by Gu Weizhang and Deng Lijia of the Institute of Chinese Medicine, Inner Mongolia Autonomous Region, Inner Mongolia Autonomous Region, we found it inappropriate. Specially proposed to discuss with the author. In this paper, it is proposed that the use of ultraviolet spectroscopy can quickly and simply determine the total content of Ophiopogon japonicus in Shengmai injection, which is obviously not appropriate. The main component of ginseng is ginsenosides (Ginsenosides). According to the structure of ginsenosides, ginsenosides can be divided into three types: ginsenoside A, B, and C. From their molecular structure, it can be seen that there is no conjugated double bond in the molecule, and therefore there is no ultraviolet absorption spectrum in the wavelength range of 200 to 400 nm. For this purpose, the gravimetric method, colorimetry, thin layer colorimetry, and the like have been used to determine the content of ginsenosides in ginseng and its preparations at home and abroad.