目的 :观察光动力疗法治疗脉络膜新生血管 (choroidalneovascularization ,CNV)性疾病患眼早期中心视野光敏感度的改变。方法 :对 2 3例 (2 3只眼 )经荧光素眼底血管造影及吲哚青绿脉络膜血管造影证实患有脉络膜新生血管性疾病的患者进行PDT治疗 ,其中湿性型老年黄斑变性 16例 (16只眼 ) ,中心性渗出性脉络膜视网膜病变 5例 (5只眼 ) ,高度近视 2例 (2只眼 )。在PDT治疗前及治疗后 3天、7天、1个月及 3个月 ,分别采用瑞士Interzeag公司Octopus10 1型全自动静态视野仪M2黄斑阈值测试程序和 32阈值测试程序 ,对各患眼中心 10°及 30°视野平均敏感度 (meansensitivity ,MS)及平均缺损 (meandefect,MD)进行测定并比较。结果 :PDT治疗后 3个月 ,2只眼 (8 70 % )视力提高≥ 2行 ,其余各眼视力无改变。与PDT治疗前比较 ,治疗后 3天、7天、1个月及 3个月黄斑区 10°MS、MD均无显著性改变 (P >0 0 5 ) ,但 7天、1个月及 3个月中心 30°视野MS较治疗前明显提高 (P <0 0 5 ) ,MD明显下降 (P <0 0 5 )。结论 :PDT治疗CNV性疾病早期可有效改善黄斑区外的视网膜光敏感性 OBJECTIVE: To observe the changes of photopic sensitivity of photocoagulation in the early central visual field of choroidal neovascularization (CNV) disease. Methods: PDT was performed in 23 patients (23 eyes) confirmed by fundus fluorescein angiography and indocyanine green choroidal angiography in 16 patients with choroidal neovascularization, including 16 cases of wet age-related macular degeneration Eyes), central exudative chorioretinopathy in 5 cases (5 eyes), high myopia in 2 cases (2 eyes). Before PDT treatment and 3 days, 7 days, 1 month and 3 months after treatment, Octopus10 type 1 automatic static vision instrument M2 macular threshold test program and 32 threshold test program of Swiss Interzeag company were respectively used to evaluate the influence of each eye center Mean sensitivities (MS) and meandefect (MD) were measured and compared at 10 ° and 30 °. Results: At 3 months after PDT, the visual acuity of 2 eyes (8 70%) was increased by 2 lines, while the rest of eyes had no change in visual acuity. Compared with pretreatment PDT, there was no significant change in 10 ° MS and MD of macular area 3 days, 7 days, 1 month and 3 months after treatment (P 0 05), but 7 days, 1 month and 3 The MS of 30 ° visual field at month center was significantly higher than that before treatment (P <0.05), and MD was significantly decreased (P <0.05). Conclusion: PDT can effectively improve the retinal light sensitivity outside the macular area in the early stage of CNV disease