Association of KCNJ5 gene missense mutations with aldosterone-producing adenoma and primary hyperald

来源 :China Medical Abstracts(Internal Medicine) | 被引量 : 0次 | 上传用户:mu_322
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Objective To detect the KCNJ5 gene variations in aldosterone-producing adenoma (APA) with primary hyperaldosteronism (PA) ,and to investigate the association of the KCNJ5 gene missense mutations with APA and PA.Methods A total of 46 APA tumors and their clinical characteristics were collected from Hypertension Center of the People’s Hospital of Xinjiang Uygur Autonomous Region,and all the tumors were confirmed by pathology. Objective To detect the KCNJ5 gene variations in aldosterone-producing adenoma (APA) with primary hyperaldosteronism (PA), and to investigate the association of the KCNJ5 gene missense mutations with APA and PA. Methods A total of 46 APA tumors and their clinical characteristics were collected from Hypertension Center of the People’s Hospital of Xinjiang Uygur Autonomous Region, and all the tumors were confirmed by pathology.
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