目的探究无创正压通气治疗急性左心功能不全肺水肿的临床疗效。方法 91例急性左心功能不全肺水肿患者,按照治疗方法不同分为对照组(45例)与观察组(46例)。对照组接受常规治疗,观察组在常规治疗基础上接受无创正压通气治疗。比较两组患者治疗效果、血气指标变化情况。结果观察组治疗总有效率为78.3%,明显高于对照组的57.8%(P<0.05)。治疗前,两组患者氧分压(Pa O_2)、二氧化碳分压(Pa CO_2)、氧饱和度(Sa O_2)比较差异无统计学意义(P>0.05)。治疗后,观察组Pa O_2、Sa O_2、Δp H明显高于对照组,Pa CO_2明显低于对照组(P<0.05)。结论无创正压通气治疗急性左心功能不全肺水肿有较好的临床疗效,可明显改善血气指标,安全可靠,值得临床推广运用。 Objective To investigate the clinical efficacy of non-invasive positive pressure ventilation in the treatment of pulmonary edema in patients with acute left ventricular dysfunction. Methods 91 cases of acute left heart failure patients with pulmonary edema, divided into control group (45 cases) and observation group (46 cases) according to different treatment methods. The control group received routine treatment, and the observation group received non-invasive positive pressure ventilation on the basis of routine treatment. Compare the treatment effect of two groups of patients, blood gas changes. Results The total effective rate of observation group was 78.3%, significantly higher than 57.8% of control group (P <0.05). Before treatment, there was no significant difference in Pa O 2, Pa CO 2 and Sa O 2 between the two groups (P> 0.05). After treatment, Pa O 2, Sa O 2 and Δp H in the observation group were significantly higher than those in the control group, Pa CO 2 was significantly lower than the control group (P <0.05). Conclusion Noninvasive positive pressure ventilation in treatment of acute left ventricular dysfunction pulmonary edema has a good clinical efficacy, can significantly improve blood gas indicators, safe and reliable, worthy of clinical promotion and use.