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周围性T 细胞(?)化成人T 细胞白血病(adult T cell leukaemia,ATL)是淋巴细胞中的周围性T 细胞(OK T_4阳性的辅助T 细胞)癌化的结果,1976年由熊本大学的高月清教授首先提出了报告。症状有发热、皮疹、全身淋巴节轻度肿胀、高血钙症、肝脾肿大以及腹水等。在发病初期或患病过程中,大多数病人都出现白血病表现。用目前治疗白血病和淋巴瘤的化学疗法均无效。预后极为不佳。近来,也报告了一些呈慢性经过的病例(慢性ATL),以及患病初期缺乏临床表现的病例(隐燃型ATL),可见ATL 的临床表现(包括典型病例乃至非典型病例)是比较复杂的。患者的年龄集中在40～60
Peripheral T-cell Adult T-cell leukemia (ATL) is a result of the carcinogenesis of peripheral T cells (OK T_4-positive helper T cells) in lymphocytes. In 1976, GAO Yueqing The professor first presented the report. Symptoms are fever, rash, generalized lymph node swelling, hypercalcemia, hepatosplenomegaly and ascites. In the early stages of illness or illness, most patients have leukemia manifestations. With the current treatment of leukemia and lymphoma chemotherapy are ineffective. The prognosis is extremely poor. Recently, some chronic cases of chronic ATL (chronic ATL) and cases of impatient ATL have been reported. The clinical manifestations of ATL (including typical and even atypical cases) are quite complicated . The patient’s age is about 40-60