论文部分内容阅读
目的探讨脑出血后早发性癫痫发作的危险因素。方法对我院2008年1月-2009年12月收治的285例脑出血患者的临床资料进行回顾性分析,对影响脑出血后早发性癫痫发作的相关临床因素进行单因素分析和Logistic回归分析。结果 285例患者中,脑出血后早发性癫痫发作的患者27例,发生率为9.47%。单因素分析结果显示,患者高血压病史、出血部位、血钠浓度、临床神经功能缺损程度评分及出血量与脑出血后早发性癫痫发作相关(P<0.05)。Logistic回归分析结果显示,患者高血压病史(OR=2.958)、出血部位(OR=4.835)、临床神经功能缺损程度评分(OR=3.073)是脑出血后早发性癫痫发作的危险因素。结论有高血压病史、皮质出血和临床神经功能缺损程度评分较高的患者,其脑出血后早发性癫痫发作的危险性较高。
Objective To explore the risk factors of premature seizure after intracerebral hemorrhage. Methods The clinical data of 285 patients with cerebral hemorrhage admitted in our hospital from January 2008 to December 2009 were retrospectively analyzed. The related clinical factors influencing the incidence of early-onset epileptic seizures after cerebral hemorrhage were analyzed by single factor analysis and Logistic regression analysis . Results Among the 285 patients, 27 cases had early-onset epileptic seizures after intracerebral hemorrhage, with a rate of 9.47%. Univariate analysis showed that the history of patients with hypertension, bleeding sites, serum sodium concentration, clinical neurological deficit score and the amount of bleeding and cerebral hemorrhage after premature seizures (P <0.05). Logistic regression analysis showed that the history of hypertension (OR = 2.958), bleeding site (OR = 4.835) and clinical neurological deficit score (OR = 3.073) were the risk factors of premature seizure after intracerebral hemorrhage. Conclusions Patients with a history of hypertension, cortical hemorrhage and a high degree of clinical neurological deficit have a higher risk of developing early-onset epileptic seizures after intracerebral hemorrhage.