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目的探讨肝硬化难治性腹水的治疗方法。方法应用腹水循环浓缩装置,一次性全腹水浓缩静脉回输治疗肝硬化腹水326例次。腹水为漏出液,鲎试验阴性,无癌细胞者可行浓缩静脉回输。每次放腹水(8960±1613)ml,浓缩至(1863±250)ml后,予以静脉回输。结果术后24h血浆白蛋白浓度明显升高,尿量显著增多,而人体电解质(血钠、血钾)、肾功能(血尿素氮)以及血液动力学(心率、平均动脉压)无明显改变。结论一次性全腹水浓缩静脉回输术是治疗肝硬化腹水一种安全、有效、经济、简单的治疗方法。
Objective To investigate the treatment of refractory ascites due to cirrhosis. Methods A total of 326 cases of cirrhotic ascites were treated with ascites circulation concentrating device and one-time all-ascites-concentrated venous return therapy. Ascites was leaking fluid, 鲎 test negative, no cancer cells viable venous return. Each ascites (8960 ± 1613) ml, concentrated to (1863 ± 250) ml, to be intravenous infusion. Results The plasma albumin concentration was significantly increased at 24 hours after operation, and the urine output was significantly increased. There was no significant change in electrolytes (serum sodium, potassium), renal function (blood urea nitrogen) and hemodynamics (heart rate, mean arterial pressure) after operation. Conclusions The disposable all-ascites concentrate venous return is a safe, effective, economical and simple treatment for the treatment of ascites due to cirrhosis.