杂环化合物是当前新药发展的主流,而在杂环化合物中则以含氮杂环为主,吡唑类化合物作为含氮杂环体系中重要一员,在农药和医药领域都表现出较好的生物活性,如杀菌、除草、杀虫、植物生长调节及抗癌等,因而颇受人们的青睐。噻唑类化合物亦是一类重要的含氮杂环化合物,具有杀虫、除草、杀菌、抗炎及抗肿瘤等生物活性,在人类保健和农业生产中扮演着十分重要的角色,并已成为药物合成研究的一个热点。目前,国内外药物化学公司相继成功 Heterocyclic compounds are the mainstream of current drug development, while heterocyclic compounds are mainly nitrogen-containing heterocycles. Pyrazoles as an important member of nitrogen-containing heterocyclic systems have shown good performance in the fields of pesticides and pharmaceuticals Of biological activity, such as sterilization, weeding, insecticide, plant growth regulation and anti-cancer, so popular with people of all ages. Thiazoles are also an important class of nitrogen-containing heterocyclic compounds that have biological activities such as insecticidal, herbicidal, bactericidal, anti-inflammatory and antitumor activities and play a very important role in human health and agricultural production and have become drugs A hot spot in synthesis research. At present, domestic and foreign pharmaceutical chemical companies have succeeded