新生儿胆红素脑病是由未结合胆红素(UCB)在脑细胞的沉淀,所引起的一种病变.早在1904年Schmol首先命名这一疾病为核黄疸以来,关于胆红素脑病的发生机制已进行了多方面的研究,但迄今尚无一种全面的,一致公认的解释.近年来对胆红素代谢的发生机制及其对神经的毒性作用,寻求新的有效防治手段以早期干预,早期预防等研究已取得某些新的进展. Neonatal bilirubin encephalopathy is a disease caused by the precipitation of unconjugated bilirubin (UCB) in brain cells.As early as 1904 Schmol first named this disease as kernicterus, Mechanism has been studied in many ways, but so far there is no comprehensive and consistent interpretation of the mechanism of bilirubin metabolism in recent years and its neurotoxic effect, to find new and effective means of prevention and treatment of early Interventions, early prevention and other research have made some new progress.