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近年来前列腺癌发病率逐年增高且呈年轻化趋势,前列腺癌根治术中海绵体神经的损伤是造成术后勃起功能障碍的主要原因,术中进行海绵体神经重建可以恢复患者术后的自发勃起。自体腓肠神经供体重建海绵体神经在临床上取得了初步成功,腹腔镜前列腺癌根治术中进行海绵体神经重建也是切实可行的;动物实验中,各种不同的供体被用于海绵体神经的重建,其中可降解生物材料结合促神经生长因子或接种活性细胞将是一种很有前途的方法。
In recent years, the incidence of prostate cancer increased year by year and the trend of younger, radical prostatectomy cavernous nerve injury is the main reason for postoperative erectile dysfunction, intraoperative cavernous nerve reconstruction can restore spontaneous erection . Autologous sural nerve donor reconstruction of cavernous nerve in the clinical preliminary success has been achieved, laparoscopic radical prostatectomy for cavernous nerve reconstruction is feasible; animal experiments, a variety of donors were used for cavernous Nerve reconstruction, in which biodegradable biomaterials bind nerve growth factor or inoculate active cells will be a promising method.