目的 :探讨桥本病与甲亢的关系 ,减少桥本病的误诊率。方法 :回顾分析 2 7例桥本病的临床表现、诊断和治疗。结果 :全组病人在化验检查前均被诊断为甲亢 ,2 5例非手术治疗 ,2 1例病人随访 2～ 3 6个月 ,8例治愈 ,11例好转 ,2例甲状腺机能减退。16例T3、T4 增高的病人经治疗后T3、T4 明显下降或恢复正常 ,2 4例TGAB、TMAB增高的病人治疗后恢复正常。结论 :桥本病女性多于男性 ,掌握其临床特点 ,结合其自身免疫球蛋白的检测 ,可以提高诊断率。必要时对可疑病人行诊断性治疗及穿刺细胞学检查 ,使病人得到有效的治疗。 Objective: To investigate the relationship between Hashimoto’s disease and hyperthyroidism and to reduce the misdiagnosis rate of Hashimoto’s disease. Methods: A retrospective analysis of 27 cases of Hashimoto’s disease clinical manifestations, diagnosis and treatment. Results: All patients were diagnosed as Hyperthyroidism before laboratory examinations. Twenty-five non-surgical treatments were performed. Twenty-one patients were followed up for 2 to 36 months. Eight were cured, 11 were improved, and two had hypothyroidism. Twenty-four patients with elevated T3 and T4 had a significant decrease or return to normal after T3 and T4, and 24 patients with elevated TGAB and TMAB returned to normal after treatment. Conclusion: Hashimoto’s disease more than men, mastered its clinical features, combined with its own immunoglobulin detection, can improve the diagnostic rate. When necessary, suspicious patients underwent diagnostic and biopsy cytology, so that patients receive effective treatment.