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垂体瘤转化基因(PTTG)是近年来从垂体组织中分离出来的原癌基因,进一步的研究发现其在多种肿瘤组织及部分正常组织细胞内高度表达,在促进细胞增殖、转化和肿瘤发生中有十分重要的作用。本文就其目前的研究进展做一综述。
Pituitary tumor transforming gene (PTTG) is a proto-oncogene isolated from pituitary tissue in recent years. Further study found that PTTG is highly expressed in many tumor tissues and some normal tissue cells, which can promote cell proliferation, transformation and tumorigenesis Have a very important role. This article reviews its current research progress.