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目的观察腹腔镜联合米非司酮治疗子宫内膜异位症的临床疗效。方法选取我院自2008年5月～2011年5月收治的60例子宫内膜异位症患者作为研究对象,按照随机数字表法随机分为观察组与对照组各30例,观察组给予腹腔镜联合米非司酮治疗,对照组单纯给予腹腔镜治疗,比较两组患者的治疗效果。结果 (1)观察组总有效率为96.7%,对照组为83.3%,两组患者总有效率比较有统计学差异(P<0.05)。(2)随访12个月,观察组复发2例,复发率为6.7%,受孕17例,受孕率为56.7%;对照组复发8例,复发率为26.7%,受孕9例,受孕率为30.0%。两组患者复发及受孕率比较均有显著差异(P<0.05),具有统计学意义。结论腹腔镜联合米非司酮治疗子宫内膜异位症可以提高治疗效果、降低复发率、提高受孕率,值得推广应用。
Objective To observe the clinical efficacy of laparoscopy combined with mifepristone in the treatment of endometriosis. Methods Sixty patients with endometriosis admitted to our hospital from May 2008 to May 2011 were selected as study subjects and randomly divided into observation group (30 cases) and control group (30 cases) according to random number table method. The observation group was given intraperitoneal Mirror combined with mifepristone treatment, the control group was given laparoscopic treatment alone, compared the treatment effect of two groups of patients. Results (1) The total effective rate was 96.7% in the observation group and 83.3% in the control group. The total effective rate of the two groups was statistically significant (P <0.05). (2) The follow-up period was 12 months. The recurrence rate was 6.7% in the observation group and 6.7% in the pregnancy group. The pregnancy rate was 56.7%. In the control group, the recurrence rate was 26.7%. The pregnancy rate was 30.0% %. Recurrence and pregnancy rates in both groups were significantly different (P <0.05), with statistical significance. Conclusion Laparoscopy combined with mifepristone treatment of endometriosis can improve the therapeutic effect, reduce the recurrence rate and improve the pregnancy rate, it is worth to promote the application.