植物源性雌激素(phytoestrogens)已被推荐用于降低人类心血管疾病危险,但现有的研究对象仅限于伴心血管病诸危险因素的非西方国家女性,且摄取含量往往较高。本文旨在就日常膳食摄入低含量植物源性雌激素与西方国家女性心血管病发病危险间关系进行了大样本前瞻分析。对象与方法受检对象为1993～1997年间的16 165例基线年龄在49～70岁之间的荷兰藉中老年女性,基线均无 Phytoestrogens have been recommended for reducing the risk of cardiovascular disease in humans, but current studies are limited to non-Western women with risk factors for cardiovascular disease and tend to have higher uptake. The purpose of this paper is to conduct a large sample prospective analysis of the relationship between dietary intake of low levels of dietary estrogen and the risk of cardiovascular disease in Western women. Subjects and methods Subjects under examination were 16,165 Dutch middle-aged and elderly women aged 49 to 70 years from 1993 to 1997 with no baseline