一、免疫疗法的历史纵观非恶性肿瘤性疾病的免疫疗法的历史,当推利用抗癌药物细胞毒作用的免疫抑制疗法为首创。此后,抗癌药物既用于治疗癌症又作为免疫疗法药物被使用。当然肾上腺皮质类固醇药物也是有效的免疫抑制剂。对各种自身免疫性疾病,特别是结缔组织疾病免疫病理机制的研究,多认为是由于免疫超强反应所致。现在则证明其部分淋巴细胞的免疫功能是低下的。就是说,由于某些特殊的淋巴细胞亚型功能低下,造成免疫最后阶段体 First, the history of immunotherapy Throughout the history of non-malignant neoplastic disease immunotherapy, when the use of anti-cancer drugs to promote the use of cytotoxic immunosuppressive therapy pioneered. Since then, anticancer drugs have been used both for the treatment of cancer and as immunotherapy drugs. Of course, adrenal corticosteroid drugs are also effective immunosuppressive agents. Of various autoimmune diseases, especially connective tissue disease immune pathological mechanism of research, and more that is due to immune super-reaction. Now that some of its lymphocytes immune function is low. That is, due to the dysfunction of some special lymphocyte subtypes, resulting in the last stage of immune