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目的 探讨生长抑素 (SS)与急性脑血管病的关系。方法 用放射免疫分析法检测 6 6例急性脑梗死 (ACI)、43例急性脑出血 (ACH)、15例急性蛛网膜下腔出血 (SAH)患者及 40例对照者的血浆 SS含量 ,同时测定部分患者及对照者的脑脊液 SS含量 ,并观察其动态变化。结果 急性脑血管病患者血浆 SS含量均高于对照组 ,其中尤以 ACI组及 SAH组比对照组差异更显著 (P<0 .0 5 ,P<0 .0 1) ,脑脊液 SS含量均显著低于对照组 (ACI组 P<0 .0 5 ,余者 P<0 .0 1) ,3周内动态观察 SS含量均无明显变化。结论 SS参与了急性脑血管病的病理生理过程
Objective To investigate the relationship between somatostatin (SS) and acute cerebrovascular disease. Methods Radioimmunoassay was used to detect plasma SS in 66 patients with acute cerebral infarction (ACI), 43 with acute cerebral hemorrhage (ACH), 15 with acute subarachnoid hemorrhage (SAH) and 40 controls. Some patients and controls cerebrospinal fluid SS content, and observe its dynamic changes. Results The levels of plasma SS in patients with acute cerebrovascular disease were significantly higher than those in the control group, especially in the ACI group and the SAH group (P <0.05, P <0.01), and the cerebrospinal fluid SS content was significantly Lower than the control group (ACI group P <0 05, the remaining P <0 01), 3 weeks of dynamic observation of SS content had no significant change. Conclusion SS participates in the pathophysiological process of acute cerebrovascular disease