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本文对６５例急性心肌梗塞（ＡＭＩ）患者随机分为卡托普利组３３例，服用卡托普利（１２．５ｍｇ，ｔｉｄ）；安慰剂组３２例，服用安慰剂。两组均在服药后第１周和第１、２、３个月各做一次二维超声心动图检查。结果：卡托普利组左室收缩末期容积指数（ＬＶＥＳＶＩ）降低（Ｐ＜０．０５），舒张末期容积指数（ＬＶＥＤＶＩ）无显著改变，每搏量指数（ＳＶＩ）和射血分数（ＥＦ）增加（均Ｐ＜０．０５）；安慰剂组ＬＶＥＤＶＩ和ＬＶＥＳＶＩ增加，ＥＦ降低（均Ｐ＜０．０５）。两组比较，至服药后第３个月，上述各指标差异均显著（Ｐ＜０．０５）。
In this study, 65 patients with acute myocardial infarction (AMI) were randomly divided into captopril group of 33 patients, taking captopril (12.5mg, tid); placebo group of 32 patients taking placebo. Two groups were in the first week and 1, 2, 3 months after taking a two-dimensional echocardiography. Results: Left ventricular end - systolic volume index (LVESVI) and left ventricular end - diastolic volume index (LVEDVI) of captopril group were significantly decreased (P <0.05) (All P <0.05). LVEDVI and LVESVI increased, while EF decreased (all P <0.05) in placebo group. There was significant difference between the two groups (P <0.05) by the 3rd month after taking the medicine.