抗菌药物在临床抗感染治疗中居有首要地位,应用最广泛,药物品种多。本文结合新近资料,仅就临床常用的抗菌药物(不包括抗肿瘤抗生素)易于发生的神经系统、肾脏、肝脏、血液系统、胃肠道、心血管系统、呼吸系统、皮肤及其它毒性反应分别作以概述.神经系统毒性反应一、耳性中毒:氨基(?)类药物能引起不同程度前庭损伤和耳聋。过去认为中毒部位可能在终末器官、耳蜗神经或中枢核。新近证明损害主要集中在耳蜗或前庭部位内外的毛细胞,硫酸链霉素,妥 Antimicrobial drugs in the clinical anti-infective treatment in the first place, the most widely used, drug varieties. In this paper, we combine the recent data only with the nervous system, kidney, liver, blood system, gastrointestinal tract, cardiovascular system, respiratory system, skin and other toxic reactions prone to the commonly used clinical antibiotics (excluding antitumor antibiotics) To summarize the nervous system toxic reactions, ear poisoning: Amino (?) Drugs can cause varying degrees of vestibular injury and deafness. In the past that the poisoning site may be in the terminal organ, cochlear nerve or central nucleus. Recently proved to damage mainly concentrated in the hair cells inside and outside the cochlear or vestibular area, streptomycin,