神经管缺陷是一种常见的出生缺陷,是造成婴幼儿死亡和患者终身残疾的主要因素之一,严重影响了人口素质〔1,2〕,为加强出生缺陷干预工作,降低神经管缺陷发生率,提高出生人口素质,根据卫生部《关于印发<增补叶酸预防神经管缺陷项目管理方案>的通知》(卫妇社发〔2009〕60号)、《浙江省农村妇女增补叶酸预防神经管缺陷项目管理方案的通知》(浙卫发254号)的文件精神,结合东阳市实际情况,从2010年4月1日起,东阳市全面实施农村妇女免费增补叶酸预防神经管缺陷项目(以下简称叶酸项目),取得了显著成效。 Neural tube defects is a common birth defects, is one of the main factors that cause infant deaths and patients with life-long disabilities, has seriously affected the quality of the population [1,2], in order to strengthen the intervention of birth defects and reduce the incidence of neural tube defects , To improve the quality of the population born, according to the Ministry of Health, “on the issuance of