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目的：探讨血清脂质水平在糖尿病（ＮＩＤＤＭ） 并发大血管病患者中的重要意义。方法：采用免疫透射比浊法及酶法测定了６３ 例糖尿病人及１００ 例健康人的血清ＴＣＨ（胆固醇） 、ＴＧ（ 甘油三脂）、ＨＤＬＣ（ 高密度脂蛋白胆固醇） 、ＬＤＬＣ（ 低密度脂蛋白胆固醇） 、ａｐｏＡ１ 、ａｐｏＢ、ａｐｏＡ１／ａｐｏＢ。结果显示：血清ＴＧ、ＬＤＬＣ、ａｐｏＢ、ａｐｏＡ１／ａｐｏＢ大血管病变组较对照组及微血管病变组显著升高，而ＴＣＨ、ＨＤＬＣ 及ａｐｏＡ１ 仅较对照组显著升高。提示：ＴＧ，ＬＤＬＣ、ａｐｏＢ及ａｐｏＡ１／ａｐｏＢ 可作为ＮＩＤＤＭ 大血管病变预测的敏感指标。临床上对于ＮＩＤＤＭ 病人应重视对脂质代谢紊乱的纠正，以尽可能避免或延缓ＮＩＤＤＭ 病人大血管并发症的发生。
Objective: To investigate the significance of serum lipid levels in patients with diabetes mellitus (NIDDM) complicated by macrovascular disease. Methods: The serum TCH (cholesterol), TG (triglyceride), HDLC (high density lipoprotein cholesterol) and LDLC in 63 cases of diabetes mellitus and 100 healthy people were measured by immunoturbidimetry and enzymatic method. (Low-density lipoprotein cholesterol), apoA1, apoB, apoA1 / apoB. The results showed: Serum TG, LDL C, apoB, apoA1 / apoB macrovascular disease group compared with the control group and microvascular lesions was significantly increased, while TCH, HDL C and apoA1 only significantly higher than the control group. Tip: TG, LDL C, apoB and apoA1 / apoB can be used as a sensitive indicator of NIDDM macrovascular disease prediction. Clinic for NIDDM patients should pay attention to the correction of lipid metabolism disorders, in order to avoid or delay the occurrence of macrovascular complications in NIDDM patients as much as possible.