目的　探讨扫描电镜技术预测良性与侵蚀性葡萄胎的应用价值 .方法　运用扫描电镜技术观察葡萄胎 90例 (良性 6 0例 ,侵蚀性 30例 ) ,以 10例正常早期胎盘绒毛作对照 .在研究方法上 ,我们把患者血、尿 HCG(绒毛膜促性腺激素 )测定作为本研究的监测指标 ,当葡萄胎后 12 wk血、尿 HCG不下降至正常时视为恶性 .结果　 16 0例良性葡萄胎的血、尿 HCG于葡萄胎后 12 wk内降至正常 ;30例侵蚀性葡萄胎中 ,2 9例 HCG于葡萄胎后 12 wk内超过正常 ,另有 1例于2 0 + 4wk超过正常 . 2良性与侵蚀性葡萄胎的扫描电镜图像有显著差别 :良性葡萄胎绒毛表面的微绒毛丰富 ,分布均匀 .侵蚀性葡萄胎绒毛表面的微绒毛相互融合 ,形成不规则斑块 .结论　扫描电镜技术可以用于预测良性与侵蚀性葡萄胎 Objective To investigate the value of scanning electron microscopy (ESEM) in the prediction of benign and invasive hydatidiform mole.Methods 90 cases of hydatidiform mole (60 cases of benign and 30 cases of erosive) were observed by scanning electron microscopy, and 10 cases of normal early placental as a control.Under the study Methods: We measured HCG (human chorionic gonadotrophin) in our study as a monitoring indicator of this study and were considered malignant when the blood glucose and urinary HCG did not fall to normal after 12 weeks of hydatidiform mole.Results Of 160 cases of benign grapes The blood and urinary HCG of the fetus decreased to normal within 12 weeks after hydatidiform mole. Among the 30 cases of invasive hydatidiform mole, 29 cases of HCG exceeded normal within 12 weeks of hydatidiform mole, and another one case exceeded normal at 20 + 4 weeks .2 There are significant differences between benign and invasive hydatidiform moles in scanning electron microscopy: the microvilli in the surface of benign hydatidiform mole are rich and evenly distributed, while the microvilli on the surface of the ervical mole are merged to form irregular plaques.Conclusion Scanning electron microscopy Technology can be used to predict benign and invasive hydatidiform moles