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作者对533例急性心肌梗塞,症状出现4小时以内的患者,进行了溶血栓疗法的随机对照研究。269例为溶血栓治疗组,264例为对照组(常规治疗)。溶血栓组在冠脉造影后立即经冠脉分次注入链激酶,直至25万单位。其中117例已在冠脉给药前经静脉给予链激酶50万单位。结果表明,溶血栓组234例接受冠脉造影者(35例未行冠脉造影),有198例冠脉内血栓被溶解,
The authors conducted a randomized controlled trial of thrombolytic therapy in 533 patients with acute myocardial infarction within 4 hours of onset of symptoms. 269 cases were treated by thrombolytic and 264 cases were treated as control. Immediately after coronary angiography, the thrombolytic group was infused with streptokinase via coronary artery fractionation until 250,000 units. One hundred and thirteen patients had been given 500,000 units streptokinase intravenously before coronary administration. The results showed that 234 cases of thrombolytic group received coronary angiography (35 cases did not underwent coronary angiography), 198 cases of coronary thrombosis were dissolved,