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呼吸道合胞病毒(RSV)是婴幼儿呼吸道感染的主要病原之一。由于其流行广泛,特别是小婴儿感染后常发生严重的毛细支气管炎和肺炎,因此其防治受到了广泛关注。近年来国外在应用含高浓度RSV中和抗体的静脉注射人血丙种球蛋白(IVIG)预防和治疗RSV的感染方面已展示了良好的前景。为了探讨行之有效的治疗方法,我们进行了国产IVIG雾化吸入治疗RSV感染的动物实验,观察国产IVIG经雾化吸入给药在体内抗RSV感染的效果,现报告如下。
Respiratory syncytial virus (RSV) is one of the major pathogens in respiratory infections in infants and young children. Because of its popularity, especially after the occurrence of severe bronchitis and pneumonia in infants, so the prevention and treatment has received widespread attention. In recent years, foreign countries have shown a good prospect in the prevention and treatment of RSV infection by intravenous injection of human blood gamma globulin (IVIG) with high concentration of RSV neutralizing antibody. In order to explore the effective treatment, we conducted a domestic IVIG aerosol inhalation treatment of RSV infection in animal experiments to observe the domestic IVIG inhalation of anti-RSV infection in vivo effect, are as follows.