壳聚糖的制备及其医院制剂的研究

来源 :中国生化药物杂志 | 被引量 : 0次 | 上传用户:q2347386
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根据壳聚糖的生物活性作用,开发壳聚糖的医院临床制剂领域。方法:利用医院现有条件将海洋动物甲壳采用高浓度碱在室温条件下长时间反应,制备壳聚糖,并研制其医院制剂。结果:经检测,医院壳聚糖制成品的脱乙酰基率达90%以上,灰分0.37%,水分0.67%,基本符合药用壳聚糖标准。根据壳聚糖的生物活性作用研制了几种医院临床制剂。结论:壳聚糖的医院制剂研究具有广阔的前景。 According to the biological activity of chitosan, the development of clinical preparations of chitosan in the field. Methods: According to the existing conditions in the hospital, the carapace of marine animals was reacted for a long time at high temperature with a high concentration of alkali to prepare chitosan and to prepare its hospital preparation. Results: After testing, the deacetyl rate of finished products of hospital chitosan was over 90%, the ash content was 0.37% and the moisture content was 0.67%, basically meeting the standard of medicinal chitosan. Several hospital clinical preparations have been developed based on the biological activity of chitosan. Conclusion: The study of chitosan in hospital preparations has broad prospects.
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