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1987～1992年,我共遇到4例在施行口腔颌面部手术中发生严重局麻药物中毒的病例。现报道其中2例: 例一:患者男,40岁;因右下颌骨体部肿物三年,诊断为右下颌骨体部囊肿而入院行手术治疗。术前检查:心肺无异常,普鲁卡因皮试阴性,既往无药物过敏史。术前半小时肌注苯巴比妥钠0.1g,常规消毒皮肤后用2％利多卡因10ml作浸润麻醉及右下牙槽神经传导阻滞麻醉,注射麻药后发现注射器内有少许血液;立即呼叫病人,呼之不应,发现病人牙关紧闭、全身抽搐,口唇及全身皮肤发绀,意识消失,自主呼吸减慢、弱;血压10.8/6.65kpa,脉搏140次/分,立即,经面罩加压给氧、输液、静注安定等处理,15分钟后生命体征恢复正常,
From 1987 to 1992, I encountered 4 cases of severe local anesthetic poisoning in the operation of oral and maxillofacial surgery. Now reported in 2 cases: Example 1: Male patient, 40 years old; due to right mandibular body mass for three years, diagnosed as right mandibular body cyst and admitted to hospital for surgical treatment. Preoperative examination: no abnormal heart and lung, procaine skin test negative, past no history of drug allergy. Half an hour before the intramuscular injection of sodium phenobarbital 0.1g, routine disinfection of the skin with 2% lidocaine 10ml infiltration anesthesia and lower right alveolar nerve block anesthesia, injection of anesthetic found a little blood within the syringe; call immediately Patients, call should not, found that the patient's teeth closed, systemic twitching, lips and systemic skin cyanosis, loss of consciousness, spontaneous breathing slow down, weak; blood pressure 10.8 / 6.65kpa, pulse 140 beats / min, Oxygen, infusion, intravenous stability and other treatment, 15 minutes after the vital signs returned to normal,