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[目的]观察五皮饮联合西药治疗肾病综合征顽固性水肿疗效。[方法]对50例住院患者采用羟乙基淀粉40氯化钠注射液500mL,1次/d,静滴;呋塞米注射液40~80mg+0.9%氯化钠注射液20mL,1次/d,静注。五皮饮(葶苈子30g,茯苓皮25g,泽泻20g,大腹皮、苏叶、苍术各15g,生姜皮、陈皮、泽泻叶、白术、厚朴各10g,桔梗8g,白蔻、砂仁各6g,沉香4g),1剂/d,水煎200mL,早晚口服。西药治疗同对照组。连续治疗30d为1疗程。观测临床症状、不良反应。治疗1疗程,判定疗效。[结果]痊愈20例,有效22例,无效8例,总有效率84.11%。[结论]五皮饮联合西药治疗肾病综合征顽固性水肿效果显著,值得推广。
[Objective] To observe the curative effect of Wupi Decoction combined with western medicine on intractable edema of nephrotic syndrome. [Method] 50 hospitalized patients were treated with hydroxyethyl starch 40 sodium chloride injection 500mL, once / d, intravenously; furosemide injection 40 ~ 80mg + 0.9% sodium chloride injection 20mL, 1 / d, intravenous injection. Wupi drink (Sipiko 30g, Poria 25g, Alisma 20g, the large belly skin, Su Ye, herb 15g, ginger skin, dried tangerine peel, Alisma orientalis, Atractylodes, Magnolia 10g, Campanulaceae 8g, Amomum 6g, Agar 4g), 1 / d, decoction 200mL, morning and evening oral. Western medicine treatment with the control group. Continuous treatment of 30d for a course of treatment. Observed clinical symptoms, adverse reactions. Treatment of a course of treatment to determine the efficacy. [Result] Twenty patients were cured, 22 were effective, 8 were ineffective and the total effective rate was 84.11%. [Conclusion] Wupi Decoction combined with western medicine has significant effect on refractory edema of nephrotic syndrome and is worth popularizing.