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目的回顾性分析宁波地区近年来临床输血患者不良反应发生情况,为临床合理用血及完善血液预警系统提供理论依据。方法对宁波地区5家综合性医院2012年10月-2014年9月期间输注各种血液成分的住院患者输血反应情况进行统计分析。结果 21 793例患者接受120 129袋红细胞悬液、冰冻血浆、机采血小板及冷沉淀成分输血,103例患者发生126人次各种输血不良反应,其中过敏性输血反应(50.8%)和非溶血性发热性输血反应(36.50%)发生率最高。4种血液成分中,输注机采血小板不良反应发生率最高,其次为冰冻血浆,红细胞悬液,冷沉淀最少。输血不良反应发生率随输血次数的增加而升高。结论严格掌握输血适应症,提高对输血不良反应的认识,对改善临床输血安全性有重要意义。
Objective To retrospectively analyze the incidence of adverse reactions in clinical transfusion patients in Ningbo in recent years and to provide a theoretical basis for clinical rational use of blood and improvement of blood early warning system. Methods The transfusion reactions of hospitalized patients with various blood components during the period from October 2012 to September 2014 in five general hospitals in Ningbo were statistically analyzed. Results A total of 21793 patients received transfusion of 120 129 red blood cells suspension, frozen plasma, apheresis and cryoprecipitate. A total of 126 blood transfusions occurred in 103 patients, of which allergic transfusion reactions (50.8%) and nonhemolytic Hemorrhagic febrile reactions (36.50%) the highest incidence. Of the four blood components, the incidence of adverse reactions of platelet transfusion was the highest, followed by frozen plasma, erythrocyte suspension and cryoprecipitate. The incidence of adverse reactions increased with the increase of blood transfusion. Conclusion Strict control of blood transfusion indications and improve understanding of the adverse reactions of transfusion is of great significance to improve the safety of clinical transfusion.