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目的：比较吡罗昔康凝胶剂和吲哚美辛擦剂对骨关节炎（ＯＡ）的疗效。方法：６０例ＯＡ病人随机分为２组，吡罗昔康组３０例（男性１４例，女性１６例；年龄５７±ｓ７ａ，病程４±４ｍｏ），每一疼痛区表面涂擦吡罗昔康凝胶１ｇ，ｑｉｄ×２ｗｋ。吲哚美辛组３０例（男性１０例，女性２０例；年龄５６±８ａ，病程２±３ｍｏ），每一疼痛区表面涂擦吲哚美辛擦剂１ｍＬ，ｑｉｄ×２ｗｋ。结果：总有效率吡罗昔康组为９０％，吲哚美辛组为７７％（Ｐ＜０．０５）。结论：吡罗昔康凝胶剂治疗ＯＡ疗效优于吲哚美辛擦剂。
Objective: To compare the efficacy of piroxicam gel and indomethacin liniment on osteoarthritis (OA). Methods: Sixty patients with OA were randomly divided into two groups: 30 patients in Piroxicam group (14 males and 16 females; age 57 ± s7a, duration 4 ± 4 months). Each pain area was treated with 1 g piroxicam gel, qid × 2wk. Indometacin group of 30 patients (10 males and 20 females; age 56 ± 8a, duration of 2 ± 3mo), each pain area smear indomethacin liniment 1mL, qid × 2wk. Results: The total effective rate was 90% in the piroxicam group and 77% in the indomethacin group (P <0.05). Conclusion: Piroxicam gels are superior to indomethacin in the treatment of OA.