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低血容量曾被认为是梗阻性黄疸时肾衰发生机制中的重要因素。为了阐明这个机制,作者对梗阻性黄疸病人的体液分布作了研究。研究组包括10个梗阻性黄疸病人,均有高结合型胆红素血症,水平为150～545μmol/L,B 超和胆道造影(经皮肝穿或逆行性)证实胆管扩张,并经剖腹探查明确了诊断。此组病人体重均减少4～15%。有胆管炎或高血压病史,已知肾衰或糖尿病的病人除外。对照组包括10例患外科良性病,体重无丢失的病人。两组病人至少研究前一周未接受输液。
Low blood volume has been considered as an important factor in the pathogenesis of renal failure in obstructive jaundice. To clarify this mechanism, the authors studied the body fluid distribution in patients with obstructive jaundice. The study group consisted of 10 patients with obstructive jaundice with hyperbilirubinemia at a level of 150-545μmol / L, bile duct dilatation confirmed by B-mode ultrasound and cholangiogram (percutaneous transhepatic or retrograde), and cesarean section by cesarean section Exploration to confirm the diagnosis. The weight of patients in this group decreased by 4 ~ 15%. Have a history of cholangitis or hypertension, except for patients with known renal failure or diabetes. The control group included 10 patients with surgical benign disease and no loss of body weight. At least two weeks before the study did not receive infusion infusion.