二甲双胍为常用的双胍类降糖药物,因其价格便宜且不加重胰岛负担,在临床上广泛应用,但其主要的不良反应是过量服用后可引起乳酸血症。因此,在临床用药过程中应加以注意。就二甲双胍不良反应的严重程度和服用注意事项,本刊记者采访了北京安贞医院的专家。 Metformin as a commonly used biguanide hypoglycemic drugs, because of its cheap and does not exacerbate the islet burden, widely used in clinical practice, but the main adverse reactions are overdose can cause lactic acidosis. Therefore, in the course of clinical medication should be noted. On the severity of adverse reactions and taking metformin precautions, this reporter interviewed Beijing Anzhen Hospital experts.