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IgA肾病是一种常见的肾小球肾炎。现已试用过皮质类固醇、免疫抑制剂、华法令、潘生丁及血浆置换等疗法,但都无确切疗效。苯妥因可降低血清IgA水平,可惜对IgA肾病并无临床和组织病理学方面的有效性。作者曾经在动物实验中发现色甘酸钠有效,遂进行该项短期的初步临床试验。 30例患者有症状的病程至少已有24个月。都经免疫萤光镜检查确诊为IgA肾病。将患者随机分为两组:
IgA nephropathy is a common form of glomerulonephritis. Has been tried corticosteroids, immunosuppressive agents, warfarin, dipyridamole and plasma exchange therapy, but no exact effect. Phenytoin can lower serum IgA levels, but unfortunately there is no clinical and histopathological validity of IgA nephropathy. The authors have found cromolyn in animal experiments effective, then the short-term preliminary clinical trial. Thirty patients had a symptomatic course of at least 24 months. Have been diagnosed IgA nephropathy by immunofluorescence microscopy. The patients were randomly divided into two groups: